List of the 200 largest US Venture Capital Single Family Offices [2025]

List of 3 large US Venture Capital Single Family Offices

In the following, we are introducing you to three interesting venture capital focused US single family offices.

1. LeFrak Family Office, New York

The investment firm „LeFrak“ manages and invests the assets of the LeFrak Family. Its history reaches back to 1901, when Harry LeFrak founded the LeFrak Organization. He started his real estate empire in that year with buying a 120-acre farm in Williamsburg, Brooklyn. The company then grew massively due to the post-War construction boom. Today the family business is held in the fourth generation and became one of the most important companies in the United States when it comes to owning, developing and managing real estate. In terms of investments LeFrak likes to focus on venture capital, but also invests in natural resources, private/public equity and of course real estate. LeFrak provides venture capital to firms with a highly entrepreneurial culture that are active in the fields of real estate, energy, health care, internet technology and software. Their current venture capital portfolio contains for example the well known e-commerce platform “wish”. Another example is “Dealpath”. This company provides a real estate industry cloud-based deal management platform. Investment and development teams leverage Dealpath as their command center for smart pipeline tracking, powerful deal analytics, and collaborative workflows to focus on value-add work that produces optimal risk-adjusted returns.

2. Dolby Family Ventures, San Francisco

Dolby Family Ventures serves as the private investment vehicle of the Dolby Family, which gained its huge fortune from the economic activities of Ray Dolby. The Family Office is also featured in our List of Single Family Offices in San Francisco. Ray was an ambitious engineer of his time who focused on the development of audio playback devices and surround sound concepts. He founded his company in 1965 and his technology remained competitive until today. For example, the Dolby Surround Technology is still used in many cinemas and high end audio devices. Dolby Family Ventures invests primary in series A venture funding in the areas of digital media, security, cloud services, health care technologies and services. One of their current portfolio companies is “Strateos”. Strateos automates chemistry, biology, and tissue analysis into closed loop robotic labs that accelerate drug discovery programs. Through a combination of best-in-class robotics and control systems, advanced software for imaging and analytics, and remote cloud laboratories, they enable their pharmaceutical partners to more rapidly and efficiently discover new drug candidates.

3. JF2 Capital Partners, Dallas

The family office of Jon Frankel (not the actor) is relatively new compared to other single family offices. It was founded in 2017 by Jon Frankel, a rather unknown entrepreneur who made his money selling two startups in the credit card processing industry. Frankel soon partnered with Aaron Pierce, a former J.P. Morgan analyst, who now helps to find deals for JF2 Capital. The investment firm prefers to fund in early rounds such as seed and series a, where the friends and family funding rounds already have passed and the companies concerned normally start to generate revenue. JF2 Capital partners are likely to invest in any geographic area, with a preference for Texas based opportunities. They don’t have a specific industry focus, but past investments show a higher interest in companies, that are active in life sciences, internet technology, sports and logistics. So is “Remedy”, for example. Remedy is a house call doctor that brings the expertise and technology of an urgent care clinic. The company uses the smartphone to bring an urgent care medical provider to the users location – home, office, or hotel. In-network with most insurances, Remedy charges a dispatch fee that has to be paid at the time of booking. Medical services are provided on-site, and billed to the users insurance.

Information included in our list

• Country of main location
• Company name
• Contact data (URL, address, state, e-mail, telephone number, executives)
• Serial letter columns for mailings (formal salutation, first name, last name of the first executive)
• LinkedIn profiles of the top management, if available
• Family information (Name, Estimated family assets in M€, Holding structure)
• Real Estate Focus (Yes/No) / Real Estate Focus Details / Examples of Real Estate Investments
• Venture Capital Focus (Yes/No) / Details on Venture Capital Focus / Examples of Venture Capital Investments
• Private Equity Focus (Yes/No) / Details on Private Equity Focus / Examples of Private Equity Investments
• Financial assets focus (Yes/No)
• Renewable Energy Focus (Yes/No)
• Other focus (art, philanthropy, forestry, agriculture, etc.)
• Dates of the entry creation, last check and last update

Values may be missing if some data points are not publicly available. The “largest single-family offices” are defined by the wealthiest American families who actively invest through investment vehicles and for whom reliable information is available. With regular, free updates and extensions, we constantly improve the data quality.